Cassava Sciences Responds to Allegations that Data is Manipulated and “Defies Logic”

Western blot analysis

Alzheimer’s drug developer Cassava Sciences found its stock down by 19% in pre-market trading Wednesday morning, following allegations against the quality and integrity of its preclinical and clinical data made in a citizen petition to the U.S. Food and Drug Administration (FDA). The petition was posted on Monday by shareholder rights law firm Labaton Sucharow.  

Texas-based Cassava, whose mission is to develop innovative treatments for neurodegenerative conditions, is developing simufilam, an investigational small molecule drug that aims to restore the normal shape and function of altered scaffolding protein, filamin A (FLNA), in the brain.

Jordan Thomas, partner and chair of the whistleblower representation practice at Labaton Sucharow, requested that federal regulators put a halt to Cassava’s clinical trials, suggesting that some of the company’s results appeared to show signs of data manipulation.

“This report raises concerns about the quality and integrity of the laboratory-based studies surrounding this drug candidate,” the

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Carl Wellman, professor emeritus of philosophy in Arts & Sciences, 94 | The Source

Philosopher Carl Wellman, the Hortense and Tobias Lewin Distinguished University Professor Emeritus in the Humanities in Arts & Sciences at Washington University in St. Louis, died of natural causes Saturday, July 17, 2021, at St. Mary’s Hospital in St. Louis. He was 94.

Wellman (left) with his wife, Farnell Parsons, and their son Christopher. (Photo courtesy of the family)

Born in 1926 in Lynn, Mass., Wellman grew up in Manchester, N.H. As a child, he fought a long battle with Steven-Johnson syndrome and after high school, at his doctors’ recommendation, studied at the University of Arizona, in hopes that the desert climate might improve his health. He earned his bachelor’s degree in 1949, double-majoring in philosophy and political science.

Wellman then pursued his doctorate in philosophy at Harvard University. He received Harvard’s Sheldon Traveling Fellowship, enabling him to spend a year at Cambridge University. There, he studied unpublished manuscripts by

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Newest American Academy of Arts and Sciences members

Ten Stanford faculty members are among the 252 new members elected to the American Academy of Arts and Sciences, which honors exceptional scholars, leaders, artists and innovators engaged in advancing the public good.

From left to right starting from the top: Axel Brunger, Tirin Moore, Chang-rae Lee, Robert Byer, Fei-Fei Li, John Etchemendy, Zhenan Bao, Yakov Eliashberg, Teresa Meng and James Mattis. (Image credit: Andrew Brodhead)

The new Stanford members to join the Class of 2021 are as follows:

Zhenan Bao, the K.K. Lee Professor in Chemical Engineering, is the department chair of Chemical Engineering. She is also a member of Stanford Bio-X and the Wu Tsai Neurosciences Institute, senior fellow at the Precourt Institute for Energy, a fellow at Stanford ChEM-H, an affiliate of the Stanford Woods Institute for the Environment and a principal investigator with the Stanford Institute for Materials and Energy Sciences at

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